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. 2017 Dec 7;9(1):1291–1301. doi: 10.18632/oncotarget.23030

Table 3. Subgroup analysis of the association between HDP and ASD.

Studies OR 95% CI
Clinical classification
Gestational hypertension 9 1.37 1.21–1.54
Pre-eclampsia 11 1.43 1.31–1.55
Chronic hypertension complicating pregnancy 4 1.48 1.29–1.70
Mixed 3 1.37 1.13–1.67
Maternal age
Higher in the case group 7 1.44 1.33–1.55
Match between case and control 7 1.29 1.11–1.50
Lower in the control group 2 1.42 1.16–1.73
Not mentioned 4 1.50 1.22–1.84
Preterm birth
Higher rate in the case group 7 1.41 1.22–1.63
Match between case and control 3 1.78 1.33–2.37
Higher rate in the control group 1 1 0.51–1.95
Not mentioned 10 1.41 1.32–1.51
Premature rupture of membranes
Higher rate in the case group 1 0.82 0.18–3.76
Match between case and control 3 0.92 0.66–1.28
Higher rate in the control group 1 1 0.51–1.95
Not mentioned 16 1.45 1.36–1.54
Maternal education
Higher in the case group 1 3.65 1.08–12.35
Match between case and control 3 1.90 1.57–2.31
Higher in the control group 2 1.26 0.80–1.99
Not mentioned 15 1.38 1.30–1.47
Geographic area
Asia 3 1.18 0.70–1.99
America 10 1.45 1.36–1.54
Europe 6 1.46 1.16–1.84
Africa 1 1.78 0.40–7.90
Oceania 2 1.17 0.94–1.45
Gender of participants
Male/female higher in case group 8 1.38 1.29–1.48
Match 9 1.68 1.42–1.99
Male/female higher in control group 0 - -
Not mentioned 4 1.44 1.19–1.74

The mixed group include pre-eclampsia, gestational hypertension and chronic hypertension complicating pregnancy.