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Viability of CXCR4+TNBC cells in co-culture with HMF and CAFs treated with a MEK inhibitor, (A) PD0325901, and a PI3K inhibitor, (B) PI-103, measured using the endogenous eGFP signal of the TNBC cells. CXCR4+TNBC cells in co-culture with CAFs show greater drug sensitivity to the molecular inhibitors. Images reflect spheroids at end of drug treatment period (5 days). Error bars represent standard error of mean. Scale bar is 200 µm. *p < 0.05.
