Figure 4. Endogenous expression of inflammasome-related genes were inhibited by XMD8-92.

(A) H2373 and (B) Hmeso mesothelioma cells were treated with XMD8-92 (40 μM) for different periods of time (24, 48 or 72 h). Cells were harvested, RNA was extracted, cDNA synthesized and expression levels of various genes were assessed using qRT-PCR (n = 2). ^*p ≤ 0.05 (t-test) as compared to vehicle control at the same time point (0). All histograms are presented as mean ± SEM.