Table 3. SCD1 inhibitor’s “druglikeness” for each candidate based # violations of to Lipinski’s Rule of 5 and Jorgensen’s Rule of 3.
| Drug candidate Compound | Rule of 5 | Rule of 3 |
| TC03.1 | 1 | 1 |
| TC03.10 | 2 | 1 |
| TC03.14 | 1 | 1 |
| TC03.15 | 1 | 1 |
| SSI-2‡ | 1 | 1 |
| TC03.18 | 2 | 1 |
| TC03.23 | 1 | 1 |
| TC03.31 | 1 | 1 |
| TC03.32 | 1 | 1 |
| TC03.33 | 2 | 1 |
| TC03.37 | 1 | 1 |
| TC03.4 | 1 | 1 |
| TC03.41 | 1 | 1 |
| SSI-3‡ | 1 | 1 |
| TC03.46 | 1 | 1 |
| TC03.47 | 1 | 1 |
| TC03.48 | 2 | 1 |
| TC03.5 | 1 | 1 |
| TC03.53 | 2 | 1 |
| TC03.56 | 1 | 1 |
| TC03.6 | 1 | 1 |
| TC03.60 | 1 | 1 |
| TC03.61 | 1 | 1 |
| TC03.66 | 2 | 1 |
| TC03.8 | 2 | 1 |
| SetA.100 control | 0 | 1 |
| SSI-4‡ | 0 | 0 |
| SetA.59 | 0 | 0 |
| SetA.61 | 0 | 0 |
| SetA.68 | 0 | 0 |
| SetA.69 | 0 | 0 |
| SetA.70 | 0 | 0 |
| SSI-1‡ | 0 | 1 |
| SetB.34 | 0 | 1 |
| SetB.49 | 0 | 0 |
| SetB.52 | 0 | 1 |
| SetB.6 | 0 | 1 |
| SetB.61 | 0 | 1 |
| SetB.66 | 0 | 1 |
| SetB.69 | 0 | 1 |
| SetB.7 | 0 | 1 |
| SetB.73 | 0 | 1 |
| SetB.74 | 0 | 0 |
| SetB.75 | 0 | 0 |