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. 2017 Aug 10;9(1):321–331. doi: 10.18632/oncotarget.20109

Figure 7. miR-761 promoted the sensitivity of colorectal cancer cells to 5-FU through targeting FOXM1.

Figure 7

(A) The expression level of FOXM1 in the olorectal cancer cell (HT29, SW480, SW620 and DLD-1) and normal colon epithelium cell line (FHC) was measured by qRT-PCR. (B) The expression of FOXM1 in the HT29 cell with FOXM1 vector was determined by qRT-PCR. (C) The response of HT29 cell to 5-FU was enhanced after treated with the FOXM1 vector compared with the cotrol-transfected cells. (D) The response of miR-761-overexpressing HT29 cell to 5-FU was rescued after transfection with the FOXM1 construct compared to the control vector. *p < 0.05; **p < 0.01 and ***p < 0.001.