Figure 8. miR-761 suppressed the colorectal cancer cell proliferation and invasion by downregulating FOXM1.
(A) Overexpression of FOXM1 rescued miR-761-overexpressing HT29 cell proliferation. (B) The mRNA expression of FOXM1 was measured by qRT-PCR. GAPDH was used as the internal control. (C) Elevated expression of FOXM1 promoted the miR-761-overexpressing HT29 cell cycle. (D) miR-761 overexpression increased the miR-761-overexpressing HT29 cell invasion. (E) The relative invasive cells were shown. *p < 0.05; **p < 0.01 and ***p < 0.001.