Table 5. Clinical characteristics based on PSA-based mass screening and clinical diagnosis.
| Clinical characteristics | Whole cohort N>984 | PSA screened N>259 | PSA screened with later diagnosis N>99 | Clinically diagnosed N>617 | P value | ||||
|---|---|---|---|---|---|---|---|---|---|
| Median age, year | 71 | 72 | 74 | 70 | P<0.0001 | ||||
| Clinical staging | |||||||||
| T staging* | P<0.0001 | ||||||||
| T1 | 53 | 5.4% | 18 | 6.9% | 4 | 4.0% | 31 | 5.0% | |
| T2 | 382 | 38.8% | 229 | 88.4% | 76 | 76.8% | 77 | 12.3% | |
| T3 | 118 | 12.0% | 6 | 2.3% | 12 | 12.1% | 100 | 16.0% | |
| T4 | 181 | 18.4% | 5 | 1.9% | 7 | 7.1% | 169 | 27.0% | |
| Missing data | 250 | 25.4% | 1 | 0.4% | 0 | 0.0% | 249 | 39.8% | |
| N staging* | N0 vs N1,2, P=0.0458 | ||||||||
| N0 | 517 | 52.5% | 140 | 54.1% | 19 | 19.2% | 358 | 57.2% | |
| N1,2 | 29 | 2.9% | 2 | 0.8% | 2 | 2.0% | 25 | 4.0% | |
| Nx | 438 | 44.5% | 117 | 45.2% | 78 | 78.8% | 243 | 38.8% | |
| M staging* | M0 vs M1, P<0.0001 | ||||||||
| M0 | 500 | 50.8% | 176 | 68.0% | 32 | 32.3% | 292 | 46.6% | |
| M1 | 242 | 24.6% | 77 | 29.7% | 65 | 65.7% | 100 | 16.0% | |
| Mx | 242 | 24.6% | 6 | 2.3% | 2 | 2.0% | 234 | 37.4% | |
| Median PSA(IQR), ng/mL | 28 | (0-1000) | 20 | (0.22-124) | 68 | (5.1-150) | 38 | (0-1000) | P<0.0001 |
| Missing data | 347 | 35.3% | 0 | 0.0% | 0 | 0.0% | 347 | 56.2% | |
| Gleason score | P<0.0001 | ||||||||
| <=6 | 206 | 20.9% | 114 | 44.0% | 22 | 22.2% | 70 | 11.2% | |
| 7 | 175 | 17.8% | 85 | 32.8% | 28 | 28.3% | 62 | 9.9% | |
| 8 | 115 | 11.7% | 31 | 12.0% | 30 | 30.3% | 54 | 8.6% | |
| 9 | 111 | 11.3% | 26 | 10.0% | 18 | 18.2% | 67 | 10.7% | |
| 10 | 24 | 2.4% | 2 | 0.8% | 1 | 1.0% | 21 | 3.4% | |
| Missing data | 353 | 35.9% | 1 | 0.4% | 0 | 0.0% | 352 | 56.2% | |
| Management approach | P=0.0049 | ||||||||
| Curative | 53 | 5.4% | 24 | 9.3% | 5 | 5.1% | 24 | 3.8% | |
| Non-curative | 931 | 94.6% | 235 | 90.7% | 94 | 94.9% | 602 | 96.2% | |
| No. of all-cause death, no. (%) | 261 | 26.5% | 60 | 23.2% | 40 | 40.4% | 161 | 25.7% | |
| No. of prostate cancer specific death, no. (%) | 217 | 22.1% | 30 | 11.6% | 37 | 37.4% | 150 | 24.0% | |
| Median follow-up time, year | 5 | (0.08-23) | 7 | (1-16) | 5 | (1-11) | 4 | (0.08-23) | P<0.0001 |
IQR, interquartile range; *Percentages may not add up to 100 due to rounding.