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. 2017 Sep 8;9(1):428–441. doi: 10.18632/oncotarget.20787

Table 5. Clinical characteristics based on PSA-based mass screening and clinical diagnosis.

Clinical characteristics Whole cohort N>984 PSA screened N>259 PSA screened with later diagnosis N>99 Clinically diagnosed N>617 P value
Median age, year 71 72 74 70 P<0.0001
Clinical staging
  T staging* P<0.0001
   T1 53 5.4% 18 6.9% 4 4.0% 31 5.0%
   T2 382 38.8% 229 88.4% 76 76.8% 77 12.3%
   T3 118 12.0% 6 2.3% 12 12.1% 100 16.0%
   T4 181 18.4% 5 1.9% 7 7.1% 169 27.0%
  Missing data 250 25.4% 1 0.4% 0 0.0% 249 39.8%
  N staging* N0 vs N1,2, P=0.0458
   N0 517 52.5% 140 54.1% 19 19.2% 358 57.2%
   N1,2 29 2.9% 2 0.8% 2 2.0% 25 4.0%
   Nx 438 44.5% 117 45.2% 78 78.8% 243 38.8%
  M staging* M0 vs M1, P<0.0001
   M0 500 50.8% 176 68.0% 32 32.3% 292 46.6%
   M1 242 24.6% 77 29.7% 65 65.7% 100 16.0%
   Mx 242 24.6% 6 2.3% 2 2.0% 234 37.4%
  Median PSA(IQR), ng/mL 28 (0-1000) 20 (0.22-124) 68 (5.1-150) 38 (0-1000) P<0.0001
  Missing data 347 35.3% 0 0.0% 0 0.0% 347 56.2%
Gleason score P<0.0001
  <=6 206 20.9% 114 44.0% 22 22.2% 70 11.2%
   7 175 17.8% 85 32.8% 28 28.3% 62 9.9%
   8 115 11.7% 31 12.0% 30 30.3% 54 8.6%
   9 111 11.3% 26 10.0% 18 18.2% 67 10.7%
   10 24 2.4% 2 0.8% 1 1.0% 21 3.4%
  Missing data 353 35.9% 1 0.4% 0 0.0% 352 56.2%
Management approach P=0.0049
 Curative 53 5.4% 24 9.3% 5 5.1% 24 3.8%
 Non-curative 931 94.6% 235 90.7% 94 94.9% 602 96.2%
No. of all-cause death, no. (%) 261 26.5% 60 23.2% 40 40.4% 161 25.7%
No. of prostate cancer specific death, no. (%) 217 22.1% 30 11.6% 37 37.4% 150 24.0%
Median follow-up time, year 5 (0.08-23) 7 (1-16) 5 (1-11) 4 (0.08-23) P<0.0001

IQR, interquartile range; *Percentages may not add up to 100 due to rounding.