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. 2017 Dec 9;9(1):607–621. doi: 10.18632/oncotarget.23078

Figure 3. Inhibition of ANO1 decreases the proliferation of breast cancer cells.

Figure 3

(A) Treatment of T16Ainh-A01, an ANO1 inhibitor, significantly inhibited the proliferation of both MCF7 and MDA-MB-231 cells in a dose-dependent manner. (B) MTT and colony-forming assays demonstrate that the knock-down of ANO1 with siRNA for ANO1 inhibited the proliferation of both MCF7 and MDA-MB-231 cells. (C) Flow-cytometry cell cycle analysis demonstrates that the G0/G1 population increases with knock-down of ANO1. *P < 0.05; **P < 0.001.