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. 2017 Dec 7;9(1):622–640. doi: 10.18632/oncotarget.23079

Table 3. List of genes related to lipid and sterol metabolism.

GOTerm_BP p-value Count Genes
Sterol Metabolic Process 4.48E-07 35 CYB5R3, LDLR, MVD, HMGCR, CYP51A1, HMGCS1, APOC1, LSS, ABCA1, C14ORF1, SCARF1, FDFT1, CYP39A1, INSIG2, DHCR7, INSIG1, PCSK9, SCARB1, CAT, NSDHL, DHCR24, SOAT1, EBP, FDPS, FDXR, SIGMAR1, ABCG1, CEL, CYP7B1, APOL1, CYP27A1, SQLE, MVK, IDI1, SC5DL
Sterol Biosynthetic Process 1.08E-06 18 CYB5R3, EBP, MVD, HMGCR, CYP51A1, HMGCS1, FDPS, LSS, C14ORF1, SIGMAR1, FDFT1, SQLE, DHCR7, MVK, IDI1, SC5DL, DHCR24, NSDHL
Cholesterol Metabolic Process 1.39E-06 32 CYB5R3, MVD, LDLR, HMGCR, CYP51A1, HMGCS1, APOC1, LSS, ABCA1, SCARF1, FDFT1, CYP39A1, INSIG2, DHCR7, INSIG1, PCSK9, SCARB1, CAT, NSDHL, DHCR24, SOAT1, EBP, FDPS, FDXR, ABCG1, CEL, CYP7B1, APOL1, CYP27A1, SQLE, MVK, IDI1
Cholesterol Biosynthetic Process 1.36E-05 14 CYB5R3, EBP, MVD, HMGCR, CYP51A1, FDPS, HMGCS1, LSS, FDFT1, DHCR7, MVK, IDI1, DHCR24, NSDHL
Lipid Biosynthetic Process 1.75E-05 74 ALDH8A1, CYB5R3, GBGT1, HMGCR, EDN1, LSS, ACSS2, C14ORF1, FDFT1, ELOVL1, PECR, ST6GALNAC6, STARD5, CYP39A1, PTGIS, ANG, ELOVL4, ELOVL3, AGPAT9, QKI, ELOVL7, SCD5, PCYT2, FGF2, PIGA, DHCR24, SPTLC3, PIGU, PIGS, CERCAM, SIGMAR1, PNPLA3, TECR, CHPT1, LPCAT4, PLAUR, SQLE, C5ORF4, PLA2G6, MVK, KGFLP1, C5DL, HSD17B11, MVD, CYP51A1, HSD3B7, CHKB, HMGCS1, MIF, ISYNA1, TPI1, CYP27B1, DHCR7, FASN, ETNK2, SCARB1, ACSL3, NSDHL, CPT1B, EBP, MOGAT2, A4GALT, FADS1, SCD, FDXR, FDPS, ACLY, CYP7B1, GGT5, P2RX7, ISPD, MBOAT2, ALOX5, IDI1, MGST2
Steroid Biosynthetic Process 2.23E-05 28 CYB5R3, HSD17B11, MVD, HMGCR, CYP51A1, HSD3B7, HMGCS1, LSS, C14ORF1, FDFT1, STARD5, CYP39A1, CYP27B1, DHCR7, SCARB1, FGF2, NSDHL, DHCR24, EBP, FDPS, FDXR, SIGMAR1, TECR, CYP7B1, SQLE, MVK, IDI1, SC5DL