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. 2017 Oct 9;9(1):691–705. doi: 10.18632/oncotarget.21672

Table 4. Top networks (IPA) enriched in the radiation induced gene expression in polysome-bound RNA [score = -log10(p-value)].

Score Top Diseases and Functions
45 Developmental Disorder, Hereditary Disorder, Metabolic Disease
43 Auditory Disease, Developmental Disorder, Endocrine System Disorders
43 Cellular Assembly and Organization, DNA Replication, Recombination, and Repair, Developmental Disorder
40 Cellular Assembly and Organization, Cellular Function and Maintenance, Cell Cycle
40 Cell Cycle, DNA Replication, Recombination, and Repair, Reproductive System Development and Function
38 Cardiovascular Disease, Developmental Disorder, Hematological Disease
38 Cellular Function and Maintenance, Nervous System Development and Function, Cell Death and Survival
38 Post-Translational Modification, Protein Folding, Lipid Metabolism
37 Drug Metabolism, Endocrine System Development and Function, Lipid Metabolism
36 Energy Production, Nucleic Acid Metabolism, Small Molecule Biochemistry
34 Cancer, Hematological Disease, Immunological Disease
32 Cellular Assembly and Organization, Developmental Disorder, Hereditary Disorder
32 RNA Post-Transcriptional Modification, Inflammatory Response, Cell Cycle
32 Developmental Disorder, Hereditary Disorder, Metabolic Disease
30 Auditory Disease, Cardiovascular System Development and Function, Cell-To-Cell Signaling and Interaction
30 Hereditary Disorder, Neurological Disease, Psychological Disorders
28 Post-Translational Modification, DNA Replication, Recombination, and Repair, Nucleic Acid Metabolism
28 Developmental Disorder, Endocrine System Disorders, Hereditary Disorder
26 Dermatological Diseases and Conditions, Developmental Disorder, Hereditary Disorder
26 Developmental Disorder, Neurological Disease, Organismal Injury and Abnormalities
26 Molecular Transport, RNA Trafficking, Cell Cycle
26 Embryonic Development, Organ Development, Organ Morphology
25 Cell Cycle, Cellular Assembly and Organization, Cellular Function and Maintenance
25 Cellular Development, Cellular Function and Maintenance, Cellular Growth and Proliferation
24 Gene Expression, Protein Synthesis, Energy Production
23 Drug Metabolism, Protein Synthesis, Free Radical Scavenging
23 Cellular Assembly and Organization, Cellular Function and Maintenance, Cell Signaling
21 Cellular Development, Cell Cycle, Connective Tissue Development and Function
21 Molecular Transport, Cell Death and Survival, Cellular Compromise
21 Cancer, Hematological Disease, Organismal Injury and Abnormalities
20 Respiratory Disease, Organismal Injury and Abnormalities, Renal and Urological Disease
19 Developmental Disorder, Hereditary Disorder, Metabolic Disease
18 Cell Death and Survival, Carbohydrate Metabolism, Lipid Metabolism
18 Gene Expression, Cellular Development, Cancer
18 Cell Morphology, Cell Cycle, Nervous System Development and Function
18 Connective Tissue Disorders, Developmental Disorder, Hematological Disease
17 Cell-To-Cell Signaling and Interaction, Cancer, Organismal Injury and Abnormalities
17 Tissue Morphology, Metabolic Disease, Cancer
17 Behavior, Cardiovascular System Development and Function, Organ Morphology
15 Cellular Development, Hematological System Development and Function, Hematopoiesis