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| Toxicity | Grade 3 | Grade 4 |
|---|---|---|
| Anemia | 5 | 1 |
| Lymphopenia | 13 | 4 |
| Neutropenia | 4 | 16 any febrile neutropenia |
| Thrombocytopenia | 3 | 2 |
| Fatigue | 4 | - |
| ALT elevation | 5 | 2 |
| AST elevation | 3 | 1 |
| Hypokalemia | 8 | - |
| Motor Neuropathy | 3 | - |
| Sensory Neuropathy | 2 | 1 |
| Thrombosis/Embolism venous? | 3 | - |
