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. 2017 Dec 6;9(1):937–957. doi: 10.18632/oncotarget.22946

Figure 5. ckit+CSCs enhance circulating levels and protein expression of IL10 in infarcted hearts following transplantation.

Figure 5

(A) Circulating levels of pro- and anti-inflammatory cytokines detected by Luminex assay 3 days following surgery in the serum of PBS treated infarcted mice used as controls (MI, n=4) and ckit+CSC transplanted infarcted mice (MI+ckit+CSCs, n=4), all normalized for their relative sham controls. Data are shown as means ± SEM. *P<0.05 vs MI. Western blot analysis showing the expression of (B) IL10 and (C) phospho-STA3/STAT3 in the infarcted region of 3 day-infarcted heart following ckit+CSC transplantation (MI+ckit+CSCs, n=3). Infarcted hearts treated with PBS were used as control (MI, n=3). Left panel: A representative Western blotting of three independent experiments is shown. Right panel: Densitometric analysis of Western blot. Data are shown as means ± SEM. *P < 0.05 vs untreated myocardial infarction (MI).