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. 2017 Dec 5;9(1):96–109. doi: 10.18632/oncotarget.22941

Table 3. Main results of the meta-analysis of the association between HLA-DQ rs9275572 polymorphism and HBV infection outcomes.

Comparison Subgroup Allele model
(A vs. G)
Heterozygous model
(AG vs. GG)
Homozygous model
(AA vs. GG)
Recessive model
(AA vs. AG+GG)
Dominant model
(AA+AG vs. GG)
OR (95%CI) PH PZ OR (95%CI) PH PZ OR (95%CI) PH PZ OR (95%CI) PH PZ OR (95%CI) PH PZ
HBV infection vs. Control Overall 0.68 (0.62-0.74) 0.11 <0.01 0.73 (0.65-0.82) 0.34 <0.01 0.45 (0.37-0.56) 0.23 <0.01 0.51 (0.42-0.62) 0.41 <0.01 0.66 (0.59-0.74) 0.21 <0.01
Asian 0.64 (0.54-0.71) 0.34 <0.01 0.68 (0.59-0.78) 0.89 <0.01 0.40 (0.31-0.52) 0.35 <0.01 0.47 (0.37-0.60) 0.46 <0.01 0.62 (0.54-0.71) 0.55 <0.01
Caucasian 0.78 (0.66-0.91) -* <0.01 0.89 (0.71-1.13) -* 0.33 0.56 (0.40-0.78) -* <0.01 0.59 (0.43-0.81) -* <0.01 0.80 (0.64-0.99) -* 0.04
HBV infection vs. NC Overall 0.70 (0.62-0.79) 0.61 <0.01 0.65 (0.56-0.76) 0.30 <0.01 0.57 (0.44-0.76) 0.99 <0.01 0.67 (0.52-0.87) 0.99 <0.01 0.63 (0.55-0.73) 0.47 <0.01
Asian 0.66 (0.57-0.76) 0.91 <0.01 0.59 (0.49-0.71) 0.92 <0.01 0.57 (0.39-0.82) 0.99 <0.01 0.70 (0.49-1.00) 0.99 0.05 0.59 (0.49-0.70) 0.94 <0.01
Caucasian 0.78 (0.64-0.94) -* 0.01 0.82 (0.61-1.09) -* 0.17 0.58 (0.38-0.88) -* 0.01 0.65 (0.44-0.95) -* 0.03 0.76 (0.58-0.99) -* 0.05
LC vs. CHB Chinese 1.34 (1.14-1.56) 0.99 <0.01 0.97 (0.80-1.18) 0.82 0.76 1.22 (0.83-1.80) 0.82 0.31 1.25 (0.85-1.82) 0.73 0.25 1.00 (0.83-1.21) 0.96 0.97
HCC vs. LC+CHB Chinese 0.71 (0.63-0.80) 0.79 <0.01 073 (0.64-0.84) 0.55 <0.01 0.49 (0.35-0.68) 1.00 <0.01 0.54 (0.39-0.76) 0.99 <0.01 0.69 (0.60-0.80) 0.63 <0.01

-*Because there was only one study with this genotype of rs9275572, the value could not be calculated.