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. 2018 Jan 24;9:51. doi: 10.3389/fimmu.2018.00051

Figure 2.

Figure 2

IgG antibody levels in children 4–9 years of age covering two booster vaccinations. (A) Pertussis toxin (PT), (B) filamentous hemagglutinin (FHA), (C) pertactin (Prn), (D) diphtheria toxoid, and (E) tetanus toxin-specific IgG levels (IU/mL) of 4- to 9-year-old whole-cell pertussis (wP)- (blue circles) or acellular pertussis (aP)-primed (red triangles) children. Blood was sampled cross-sectionally at 4 years of age before, 1 month, and 2 years (6 years of age) after the preschool diphtheria, tetanus, and aP booster and from different children longitudinally at 9 years of age before, 1 month, and 1 year after the preadolescent Tdap booster. Note, black lines indicate geometric mean concentration with 95% confidence interval, *p-value <0.05, and **p-value <0.01. Note, data of PT, FHA, and Prn for wP-primed children aged 4–9 years and aP-primed children aged 4–6 years were previously published (25, 26).