Figure 4.

Comparison of early vs. late pre-onset treatment on animal survival. (A) Distribution of data points for time bin determination. The “early” pre-onset treatment group included mice that started treatments before day 42, and the “late” pre-onset treatment group consisted of mice that started treatments after day 42 (see Methods section Statistical Analysis). (B) Mean survival day for the early treatment group compared to late treatment group. A Mann Whitney U-test showed no statistically significant difference between the early and late pre-onset treatment groups.