Table 3.
Comparative analysis between non alcoholic fatty liver disease and other than non alcoholic fatty liver disease
| Variable | NAFLD n = 81 (11.4%) | Non-NAFLD n = 627 (88.6%) | P value |
| Age, yr (± SD) | 63 ± 8 | 62 ± 4 | 0.39 |
| Gender, male, n (%) | 68 (83.9) | 469 (74.9) | 0.06 |
| Non-cirrhotic liver, n (%) | 7 (8.6) | 62 (9.9) | 0.72 |
| Child Pugh A/B/C, n (%) | 41 (50.6)/32 (39.5)/8 (9.9) | 311 (49.6)/206 (32.8)/110 (17.5) | 0.15 |
| Comorbidities, n (%) | 60 (74.1) | 239 (38.1) | < 0.0001 |
| Diabetes mellitus, n (%) | 50 (61.7) | 146 (23.3) | < 0.0001 |
| Median AFP level, ng/mL | 6.6 (4-380) | 26 (5.3-332) | 0.017 |
| AFP > 1000 ng/mL, n (%) | 9 (12.0) | 97 (16.1) | 0.34 |
| Ascites, n (%) | |||
| Mild | 17 (21.0) | 127 (20.3) | 0.7 |
| Moderate-severe | 10 (12.3) | 99 (15.8) | 0.7 |
| Encephalopathy, n (%) | |||
| Grade I-II | 18 (22.2) | 119 (19.0) | 0.2 |
| Grade III-IV | 3 (3.7) | 7 (1.1) | 0.2 |
| Esophageal varices, n (%) | 50 (63.3) | 344 (55.8) | 0.5 |
| ECOG 0-2, n (%) | 73 (90.1) | 564 (89.9) | 0.96 |
| Median HCC number, (IQR) | 1 (1-2) | 1 (1-2) | 0.38 |
| Largest HCC diameter, mm (IQR) | 55 ± 37 | 52 ± 37 | 0.51 |
| Within Milan, n (%) | 38 (46.9) | 295 (47.0) | 0.98 |
| Bilobar involvement, n (%) | 16 (19.7) | 142 (22.7) | 0.82 |
| Diffuse HCC pattern, n (%) | 3 (3.7) | 20 (3.2) | 0.82 |
AFP: Alpha-fetoprotein; MELD: Model for end stage liver disease; AFLD: Alcoholic fatty liver disease; Non-NAFLD: Other than NAFLD (includes all other etiologies).