Table 4.
Univariate and multiple logistic regression for the secondary outcome of any thrombosis after liver transplantation
| Variable |
Univariate logistic regression, n = 65 |
Multiple logistic regression, n = 62 |
||
| Odds ratio (95%CI) | P-value | Odds ratio (95%CI) | P-value | |
| Yr | 0.96 (0.81, 1.14) | 0.656 | ||
| Weight | 0.74 (0.53, 1.03) | 0.075 | ||
| PELD | 0.97 (0.93, 1.02) | 0.218 | ||
| Surgeon 2 vs 1 | 1.50 (0.37, 6.03) | 0.568 | ||
| Surgeon 3 vs 1 | 7.20 (1.75, 29.57) | 0.006 | 8.66 (0.99, 75.63) | 0.051 |
| Surgeon 2 vs 3 | 0.21 (0.05, 0.88) | 0.033 | ||
| Surgery duration, n = 591 | 0.99 (0.98, 1.00) | 0.017 | ||
| Fascia closed on admission | 2.55 (0.84, 7.78) | 0.1 | ||
| Hepatic artery any comment2 | 2.55 (0.84, 7.78) | 0.1 | ||
| Biliary anatomy comment2 | 5.12 (1.08, 24.20) | 0.039 | ||
| Any operating note comment | 3.44 (0.99, 11.94) | 0.052 | ||
| Lowest anti-thrombin d2-5, n = 62 | 0.95 (0.91, 1.00) | 0.03 | 0.93 (0.87, 0.99) | 0.038 |
| First day use of furosemide, n = 541 | 1.24 (1.04, 1.47) | 0.018 | ||
| Graft type R/SL vs WL | 0.12 (0.03, 0.54) | 0.006 | 0.10 (0.01, 0.85) | 0.034 |
| Graft type LR vs WL | 0.10 (0.03, 0.44) | 0.002 | 0.10 (0.01, 0.71) | 0.021 |
If multiple regression is done with first day furosemide (n = 54) a trend for first day of furosemide [OR 1.37 (0.99, 1.90), P = 0.062] is found, meaning the later the furosemide is started, the higher the risk of thrombosis;
“Any operating note comment” was used as it is collinear with “hepatic artery any comment” and “biliary anatomy comment”. If instead, we remove “any operating note comment” and add “hepatic artery any comment” and “biliary anatomy comment”, there is no meaningful change to the regression results. LR: Living related liver graft; OR: Odds ratio; PELD: Pediatric end-stage liver diseases score; R/SL: Reduced or split liver graft; WL: Whole liver graft.