Table 6. Predictors of intracranial hemorrhage with odds ratio and 95% confidence interval for ICH in patients with LVAD (multivariate analysis).
| Predictors of ICH | Odds ratio | Lower limits of 95% CI | Upper limits of 95% CI | P values |
|---|---|---|---|---|
| Age (years) | ||||
| [18–35] vs. [51–65] | 2.4 | 1.2 | 4.7 | 0.01 |
| [36–50] vs. [51–65] | 0.9 | 0.4 | 1.7 | 0.6 |
| 66+ vs. [51–65] | 0.6 | 0.3 | 1.2 | 0.1 |
| Male vs. female | 1.056 | 0.645 | 1.730 | 0.8 |
| Race | ||||
| Black vs. White | 1.406 | 0.676 | 2.925 | 0.4 |
| Hispanic vs. White | 0.957 | 0.268 | 3.416 | 0.9 |
| White vs. other | 1.178 | 0.625 | 2.221 | 0.6 |
| CCI | ||||
| 0–1 vs. 3 | 0.002 | 0.001 | 0.012 | <0.0001 |
| 2 vs. 3 | 0.075 | 0.043 | 0.130 | <0.0001 |
| 4 vs. 3 | 8.303 | 3.959 | 17.412 | <0.0001 |
| Abnormal coagulation profile | 1.415 | 0.653 | 3.064 | 0.4 |
| HTN | 0.826 | 0.463 | 1.473 | 0.5 |
| PVD | 0.118 | 0.038 | 0.363 | 0.0002 |
| Chronic lung disease | 0.073 | 0.036 | 0.149 | <0.0001 |
| DM | 0.053 | 0.024 | 0.116 | <0.0001 |
| Liver disease | 0.936 | 0.634 | 1.347 | 0.8 |
| Renal disease | 0.87 | 0.45 | 1.68 | 0.9 |
| Valvular disease | 0.594 | 0.305 | 1.156 | 0.1 |
| LVAD implantation in: previous vs. index admission | 1.005 | 0.622 | 1.624 | 0.9 |
| Year | ||||
| 2007 vs. 2011 | 2.831 | 1.053 | 7.616 | 0.04 |
| 2008 vs. 2011 | 1.211 | 0.578 | 2.538 | 0.6 |
| 2009 vs. 2011 | 0.948 | 0.410 | 2.194 | 0.9 |
| 2010 vs. 2011 | 1.196 | 0.648 | 2.206 | 0.6 |
LVAD, left ventricular assist device; ICH, intracranial hemorrhage; CCI, Charlson Comorbidity Index; HTN, hypertension; PVD, peripheral vascular disease; DM, diabetes mellitus.