Table 1.

Apparent average rates (min⁻¹) of exchange, k_HDX, from fits to HDXMS data (at 10 °C) for peptides affected by OS

Apparent average rate constants were determined from one- or two-exponential fits to the data within the dynamic range of the measurement. The rates are represented within one S.D. from the exponential fits to the data. For complete rate constant analysis across all temperatures, see Table S1; Arrhenius plots are shown in Fig. 7 for reference.

Peptide	SLO (without OS)	SLO (with OS)
1–14	0.066 ± 0.008	0.06 ± 0.01
239–256	0.3 ± 0.1	2.1 ± 0.9
257–273	0.11 ± 0.07	2.8 ± 0.9
297–305	0.10 ± 0.02	1.0 ± 0.2
306–316	0.14 ± 0.04	0.9 ± 0.1
317–334	0.009 ± 0.004	0.08 ± 0.02
751–761	0.06 ± 0.02	1.1 ± 0.4