Oxygenation properties of human HbA, HbS, and DCLHb after adsorption on SNPs. Oxygen partial pressure at half saturation P50 (A) and Hill coefficient n (B) of HbA, DCLHb, HbS in 0.1 M phosphate buffer at pH 7.4, and HbA in 0.1 M BisTris-HCl buffer at pH 6.0, with and without SNPs. The black line represents the limit of cooperative oxygen binding (n > 1).