Table 2.
Endophthalmitis after PK: Causative organisms, Age of PK, Interval from Last Surgical Procedure to Diagnosis, Risk factors, and Follow-Up Data.
| Case | Duration of PK (days) | Sutures present | Lens status | Organism | Follow-up Post-Infection (months) | Last Recorded VA | Primary treatment | Further Surgical Intervention |
|---|---|---|---|---|---|---|---|---|
| 1 | 240 | Yes | IOL | Staphylococcus epidermidis | 0.3 | 20/400 | TAP V/C/D | None |
| 2 | 9 | Yes | IOL/open posterior capsule | Streptococcus oralis | 12.0 | HM | TAP V/C | Secondary PPV for worsening (PK removal/Temp Kpro/IOL removal/PPV/IV V/C/Vori/PK), late RD repair, Kpro/SOI for graft rejection |
| 3 | 2 | Yes | IOL/open posterior capsule | Streptococcus agalactiae | 1.1 | LP | PPV V/C/D | Secondary PPV for worsening |
| 4 | 262 | Yes | IOL | Staphylococcus epidermidis | 13.5 | 20/800 | TAP V/C/D | Late PPV/SB/AFX for RD |
| 5 | 216 | Yes | IOL/open posterior capsule | Staphylococcus epidermidis | 8.9 | 20/70 | TAP V/C/D | None |
| 6 | 5 | Yes | ACIOL/open posterior capsule | Staphylococcus epidermidis | 135.2 | LP | TAP V/C | Repeat TAP with IV Vanco, Late repeat PK for wound dehiscence and external drainage of HCD |
| 7 | 924 | No | IOL | Staphylococcus hominis | 64.0 | 20/200 | TAP V/C | None |
| 8 | 6 | Yes | IOL/open posterior capsule | Enterococcus faecalis | 38.7 | 20/800 | TAP V/C/D | GDI |
| 9 | 36 | Yes | IOL/open posterior capsule | Candida Albicans | 99.6 | 20/100 | TAP V/C | Secondary PPV with IV Ampho for worsening, AC washout ×2 with Vori/Ampho, late repeat PK for graft rejection |
| 10 | 17 | Yes | Aphakic/open posterior capsule | Methicillin resistant staphylococcus aureus | 13.7 | HM | TAP V/C | Secondary PPV for worsening |
| 11 | 212 | Yes | Crystalline lens | Pseudomonas aeruginosa | 6.2 | NLP | TAP V/C/D | Repeat TAP with IV Ceftaz |
AC = anterior chamber; ACIOL = anterior chamber intraocular lens; AFX = air fluid exchange; Ampho = intravitreal Amphoteracin B; C/Ceftaz = intravitreal Ceftazidime; D = intravitreal Dexamethasone HM = hand motions; GDI = glaucoma drainage implant; HCD = hemorrhagic choroidal detachment; IOL = intraocular lens; IV = intravitreal; KPro = keratoprosthesis; LP = light perception; NLP = no light perception; PK = penetrating keratoplasty; PPV = pars plana vitrectomy; RD = retinal detachment; SB = scleral buckle; SOI = silicone oil injection; TAP = vitreous paracentesis and intravitreal injection; Temp KPro = temporary keratoprosthesis; V/Vanco = intravitreal Vancomycin; Vori = intravitreal Voriconazole.