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. 2017 Dec 22;10:269–276. doi: 10.1016/j.omtn.2017.12.011

Figure 4.

Figure 4

Role of lncRNAs in ALS

lncRNA could recruit FUS/TLS to the genomic locus that encodes cyclin D1, where cyclin D1 transcription is repressed in response to DNA damage signals, resulting in increased tolerance to apoptosis signals.