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A summary of HDR-derived gene-editing on RAG2 locus. This is a summary of three independent replicates. A total of 154 embryos were injected and 28 embryos reached blastocysts on d 7. From 23 blastocysts genotyped, two embryos presented homozygous HDR-derived alleles (8.69%) and seven embryos carried heterozygous HDR-derived alleles (30.4%)
| Type of gene-editing events | Frequency, % |
|---|---|
| Homozygous HDR | 8.69 |
| Heterozygous HDR | 30.4 |
| No HDR | 60.8 |
