Table 3.

Summarized results of different studies comparing choroidal thickness measurements of healthy pregnant and non-pregnant women using EDI-OCT

References	Subjects	Gestational age at exam	Mean subfoveal choroidal thickness (SFCT)	Conclusion
Takahashi et al. [27]	30 pregnant women 30 non-pregnant women	Third trimester	275 ± 84 µm 273 ± 92 µm	No significant difference in choroidal thickness between groups (p = 0.925)
Sayin et al. [25]	46 pregnant women 40 non-pregnant women	Variable 28.0 ± 5.8 weeks (range: 17–37 weeks)	368.6 ± 67.6 µm 334.8 ± 59.9 µm	SFCT in normal pregnant women was significantly thicker than in non-pregnant healthy women (p = 0.038)
Kara et al. [24]	100 pregnant women 100 non-pregnant women	Variable 27.3 ± 6.6 weeks (range: 15–38 weeks)	371.1 ± 61.8 µm 337.2 ± 62.4 µm	SFCT in normal pregnant women was significantly thicker than in non-pregnant healthy women (p < 0.01)
Atas et al. [26]	25 pregnant women 26 non-pregnant women	Over 28 weeks	387.2 ± 60.76 µm 322.35 ± 63.89 µm	SFCT in normal pregnant women was significantly thicker than in non-pregnant healthy women (p < 0.001)
Goktas et al. [29]	30 pregnant women in the first trimester 30 pregnant women in the second trimester 30 pregnant women in the third trimester 30 non-pregnant women	First trimester Second trimester Third trimester	362 ± 81 µm 395 ± 80 µm 368 ± 70 µm 335 ± 86 µm	SFCT was significantly thicker in pregnant women in the second trimester (p = 0.007)
Ulusoy et al. [16]	29 pregnant women 36 non-pregnant women	Third trimester 3 months after delivery	387.97 ± 59.91 µm 332.40 ± 26.02 µm 320.86 ± 59.18 µm	SFCT significantly increases during pregnancy and returns to normal range 3 months after delivery
Kim et al. [21]	14 pregnant women 21 non-pregnant women	Third trimester	274.23 ± 29.30 µm 264.95 ± 21.03 µm	No significant difference in choroidal thickness between groups (p = 0.325)
Dadaci et al. [30]	27 pregnant women 25 non-pregnant women	First trimester Third trimester	OD: 349.22 ± 82.11 µm OE: 341.30 ± 85.22 µm OD: 333.56 ± 76.61 µm OE: 326.93 ± 75.84 µm OD: 318.88 ± 53.13 µm OE: 310.60 ± 51.09 µm	Choroidal thickness measurements in the third trimester were significantly decreased in both eyes compared to first trimester measurements
Rothwell et al. [31]	12 pregnant women 12 non-pregnant women	Third trimester	319.58 ± 6.11 µm 287.58 ± 43.44 µm	Choroidal thickness in normal pregnant women was significantly thicker than in non-pregnant healthy women (p = 0.034)
Acmaz et al. [32]	24 pregnant women 38 non-pregnant women	After 24 weeks	393.77 ± 61.83 µm 322.49 ± 65.58 µm	Choroidal thickness in normal pregnant women was significantly thicker than in non-pregnant healthy women (p < 0.001)