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. 2018 Jan 29;11:5. doi: 10.1186/s13072-018-0176-2

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Transcription factor binding and histone modifications at a subset of TDG-targeted genes. Genomic regions surrounding genes identified as having E2-dependent TDG binding and increased transcription show precise overlap of TDG, ER and a subset of ENCODE transcription factors. Additionally, overlap with datasets containing histone ChIP-Seq data reveals the enrichment of histone marks corresponding to active/poised enhancers and depleted of those markings found at repressed/silenced enhancers (SM standard media)