Table 1.
Virus antigen | HI titerb
|
Neut. titerb
|
||
---|---|---|---|---|
Sera raised against
|
Sera raised against
|
|||
DK/96-WT | DK/96-Hu | DK/96-WT | DK/96-Hu | |
DK/96-wt | 121(80–160) | 134(80–160) | 320(160–640) | 452(320–640) |
DK/96-Hu | 52(20–80) | 67(40–80) | 425(160–640) | 761(640–1280) |
Convalescent serum samples from individual mice (5 per group) are collected 21 days post-inoculation with 106 EID50 of the virus indicated.
Samples are tested for HI and neutralization antibody activity against either DK/96-wt or mutant DK/96-Hu virus. Geometric mean titers (with range in parentheses) are shown as the reciprocal of the highest dilution of serum that completely inhibits haemagglutination (HI) or that neutralizes 100 PFU of infectious virus (neut).