. Author manuscript; available in PMC: 2018 Jan 29.

Published in final edited form as: Virology. 2014 Jul 30;464-465:156–165. doi: 10.1016/j.virol.2014.07.004

Table 2.

Geometric mean of hemagglutination-inhibition (HI) and neutralizing (neut) antibody titers of mice vaccinated with two-doses of DK/96-wt or DK/96-Hu inactivated virus vaccine.

Virus antigen	Vaccine dose (μg)	HI titers of mouse sera against^a
DK/96-wt		DK/96-wt^b		DK/96-Hu^b
DK/96-wt		HI titer	Neut. titer	HI titer	Neut. titer
	10	320	253	289	296
	5	293	172	320	242
	2.5	274	nd	320	320 nd

Mice receive a two-dose regimen of the indicated vaccine 4 weeks apart. Serum samples from individual mice (10 per group) are collected 30 days post-boost. Nd=not done.

Samples are tested for HI and neutralization antibody activity against DK/96-wt virus. Geometric mean titers are shown as the reciprocal of the highest dilution of serum that completely inhibits hemagglutination (HI) or that neutralizes 100 PFU of infectious virus (neut). There is no significance in titers between DK/96-wt and DK/96-Hu groups by two-way ANOVA and Bonferroni post-test.