Table 3.
Minimum inhibitory concentration of the hit compound against clinically important bacterial.
| Bacteria | Isopomiferin |
|---|---|
| E. coli (ATCC 25922) | 128a |
| E. coli tolC (efflux mutant) | 64 |
| E. faecalis (ATCC 29212) | 32 |
| H. influenzae (ATCC 49766) | 32 |
| P. aeruginosa (ATCC 47085) | 128 |
| P. aeruginosa PAO200 (efflux mutant) | 128 |
| P. aeruginosa (hypersensitive) | 16 |
| S. aureus (ATCC 29213) | 32 |
| S. pneumoniae (ATCC 49619) | >128 |
a
The MIC (μg/ml) against each of the bacteria was determined in three separate sets of assays.