Table 1.
A selection of ABCG2 substrates and inhibitorsa
| Substrates | Inhibitors |
|---|---|
|
| |
| 5-fluorouracil | atazanavir |
| abacavir | chromanone derivatives |
| atorvastatin | curcumin |
| azidopine | cyclosporin A |
| ciprofloxacin | delavirdine |
| daunorubicin | fumitremorgin C (FTC) Ko143 |
| doxorubicin | itraconazole |
| efavirenz | ketoconazole |
| epirubicin | lopinavir |
| erlotinib | nelfinavir |
| erythromycin | poloxamines |
| etoposide | reserpine |
| flavopiridol | ritonavir |
| fluvastatin | saquinavir |
| folic acid | sirolimus |
| ganciclovir | tacrolimus |
| gefitinib | |
| glutathione | |
| glyburide | |
| homocamptothecins | |
| imatinib | |
| irinotecan | |
| lamivudine | |
| methotrexate | |
| mitoxantrone | |
| nilotinib | |
| pantoprazole | |
| pheophorbide A | |
| PhIP | |
| pitavastatin | |
| porphyrins | |
| pravastatin | |
| riboflavin | |
| rosuvastatin | |
| SN-38 | |
| sorafenib | |
| sulfasalazine | |
| sulfated estrogens | |
| sunitinib | |
| tamoxifen | |
| tariquidar | |
| topotecan | |
| urate | |
| vitamin K3 | |
| zidovudine | |