Table 1.
Baseline and 12-Week Health Status Scores Stratified by Treatment Arm
| Variable | HLSE | CPAP | NSO | |
|---|---|---|---|---|
| Vitality | ||||
| N | 100 | 99 | 101 | |
| Baseline | 48.5±10.6 | 48.2±11.4 | 47.3±10.1 | |
| 12 week | 49.5±9.4 | 51.8±11.1 | 49.8±9.0 | |
| Change from baseline | 1.0±8.4 | 3.6±9.4 | 2.5±8.3 | |
| P value | 0.2314 | 0.0002 | 0.0038 | |
| Physical Function | ||||
| N | 99 | 99 | 101 | |
| Baseline | 44.0±9.1 | 45.1±10.4 | 42.0±11.3 | |
| 12 week | 43.7±9.7 | 44.2±11.9 | 44.4±10.6 | |
| Change from baseline | −0.3±6.8 | −0.9±6.9 | 2.3±8.1 | |
| P value | 0.6246 | 0.2020 | 0.0047 | |
| MCS | ||||
| N | 99 | 99 | 100 | |
| Baseline | 48.9±12.3 | 48.9±11.0 | 51.4±12.5 | |
| 12 week | 49.7±11.0 | 52.6±10.0 | 51.9±10.1 | |
| Change from baseline | 0.8±8.1 | 3.7±8.2 | 0.5±8.8 | |
| P value | 0.3342 | <.0001 | 0.5984 | |
| PCS | ||||
| N | 99 | 99 | 100 | |
| Baseline | 43.6±9.0 | 44.7±9.5 | 41.6±9.2 | |
| 12 week | 42.9±9.3 | 44.6±10.2 | 44.1±10.5 | |
| Change from baseline | −0.8±6.4 | −0.1±5.1 | 2.4±6.2 | |
| P value | 0.2211 | 0.8275 | 0.0002 | |
| Role Physical | ||||
| N | 100 | 99 | 100 | |
| Baseline | 43.9±10.2 | 44.7±11.5 | 44.5±11.0 | |
| 12 week | 43.5±9.5 | 46.7±11.0 | 45.7±11.1 | |
| Change from baseline | −0.4±8.7 | 2.1±7.1 | 1.2±8.8 | |
| P value | 0.6284 | 0.0051 | 0.1670 | |
| Role Emotional | ||||
| N | 100 | 99 | 100 | |
| Baseline | 46.0±12.6 | 45.7±11.8 | 47.9±12.4 | |
| 12 week | 45.8±11.9 | 47.9±10.5 | 48.3±11.1 | |
| Change from baseline | −0.2±10.5 | 2.2±8.2 | 0.3±11.1 | |
| P value | 0.8540 | 0.0093 | 0.7528 | |
| Social Functioning | ||||
| N | 100 | 99 | 101 | |
| Baseline | 47.2±10.8 | 47.6±11.7 | 47.5±10.8 | |
| 12 week | 46.8±11.5 | 49.4±10.6 | 49.2±9.9 | |
| Change from baseline | −0.4±9.6 | 1.7±7.8 | 1.7±8.2 | |
| P value | 0.6916 | 0.0321 | 0.0366 | |
| Bodily Pain | ||||
| N | 100 | 99 | 101 | |
| Baseline | 46.7±10.5 | 46.8±10.2 | 44.8±8.3 | |
| 12 week | 45.7±10.6 | 47.5±11.0 | 47.0±10.0 | |
| Change from baseline | −1.1±8.8 | 0.7±7.6 | 2.3±7.6 | |
| P value | 0.2321 | 0.3500 | 0.0036 | |
| Mental Health | ||||
| N | 100 | 99 | 101 | |
| Baseline | 48.6±10.8 | 49.2±10.3 | 51.0±10.4 | |
| 12 week | 49.4±10.2 | 52.4±9.5 | 51.6±9.4 | |
| Change from baseline | 0.8±7.7 | 3.2±8.3 | 0.5±8.0 | |
| P value | 0.2729 | 0.0002 | 0.5131 | |
| General Health | ||||
| N | 100 | 99 | 101 | |
| Baseline | 43.4±9.7 | 44.9±10.9 | 43.6±8.8 | |
| 12 week | 43.3±9.3 | 46.3±9.8 | 45.2±10.0 | |
| Change from baseline | −0.1±6.1 | 1.5±6.9 | 1.6±5.8 | |
| P value | 0.8549 | 0.0391 | 0.0081 | |
| PHQ-9 | ||||
| N | 100 | 99 | 101 | |
| Baseline | 6.3±5.1 | 5.2±4.7 | 5.3±5.3 | |
| 12 week | 5.1±4.0 | 3.5±4.1 | 4.2±4.0 | |
| Change from baseline | −1.1±3.8 | −1.7±3.6 | −1.1±4.1 | |
| P value | 0.0037 | <.0001 | 0.0081 | |
| Sleepiness Summary Score | ||||
| N | 98 | 96 | 100 | |
| Baseline | 6.3±2.9 | 6.2±3.0 | 6.2±2.8 | |
| 12 week | 5.6±2.9 | 4.3±2.7 | 4.6±2.8 | |
| Change from baseline | −0.8±2.5 | −1.9±2.9 | −1.6±3.0 | |
| P value | 0.0036 | <.0001 | <.0001 | |
HLSE-Healthy lifestyle, sleep hygiene and education intervention; CPAP-Continuous positive airway pressure; NSO-Nocturnal supplemental oxygen. Categorical data represented as percentage of population and continuous data represented as mean (standard deviation); SF-36-Short Form-36; MCS-mental component score; PCS-Physical component score; PHQ-9-Patient Health Questionnaire-9. All SF-36 scores are norm-based with ranges from 0–100 with higher score representing better quality of life.