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. 2018 Jan 21;14:1744806917754142. doi: 10.1177/1744806917754142

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© The Author(s) 2018

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Mu opioid receptor-dependent analgesic effect of lithium chloride on neuropathic mice. (a) Effect of naloxone (0.1 mg/kg, s.c.) on lithium-induced analgesia (100 mg/kg, i.p.; n = 6 per group; two-way ANOVA test with a Bonferroni correction; ^$p < 0.01). (b) Effect of lithium chloride on MOR null neuropathic mice (n = 6 per group, ANOVA test; n = 6. ns: non-significant). Values are means ± SEM. Pretesting group corresponds to mechanical threshold before lithium and/or naloxone injections. The 4-h group corresponds to mechanical threshold observed 4 h after lithium and/or naloxone injections. MOR: mu opioid receptor.