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. 2017 Dec 8;8(2):73–92. doi: 10.1177/2045125317743435

Table 2.

DBS for anorexia nervosa patients. This table illustrates 25 cases of DBS for anorexia nervosa. All 25 patients were adult female patients who underwent DBS targeting the NAc, SCC, VC/VS, or BNST. All of the studies, except for the VC/VS and BNST (no follow up for the VC/VS study, decrease in weight with the BNST study) studies, demonstrated an increase in BMI with DBS.

Study Target Stimulation parameters Number of patients Age Gender Initial BMI BMI after DBS Follow up (months) Comorbidities
Wang and colleagues124 NAc 135–185 Hz, 120–210 µs pw, 2.5–3.8 V 2 18–28 Female 12.9–13.3 18–21 12 (1) OCD, depression, anxiety; (2) depression, anxiety
Wu and colleagues125 NAc 180 Hz, 90 µs pw 4 16–17 Female 10–13.3 17–22 9–50 (1) OCD; (2) OCD; (3) OCD; (4) Anxiety disorder
Israel and colleagues126 SCC Right-sided: 130 Hz, 91 µs pw, 5 mA 1 52 Female 14.4 19 30 Depression
Lipsman and colleagues,127 Lipsman et al.128 SCC 130 Hz, 90 µs pw, 5–6 V 16 34 Female 13.8 ± 1.5 17.3 ± 3.4 12
McLaughlin and colleagues 119 VC/VS 120 Hz, 120 µs pw, 7.5 V 1 52 Female 18.5 OCD, depression
Blomstedt and colleagues129 BNST 130 Hz, 120 µs pw, 4.3 V 1 60 Female 15.2 14.3 12

BNST: bed nucleus of stria terminalis; NAc: nucleus accumbens; OCD: obsessive-compulsive disorder; pw: pulse width; SCC, subgenual cingulate cortex; VC/VS: ventral capsule/ventral striatum.