Figure 3.
Receiver operating characteristic (ROC) analyses of isolated, perfused guinea-pig hearts and patients recovering from coronary revascularization surgery on cardiopulmonary bypass. (a) Isolated guinea-pig hearts: Analyses of mean values of contractile function and myocardial energy state from 42 separate series3,7,30,43,138,139 comprising approximately 210 isolated hearts metabolizing glucose alone, glucose + lactate or glucose + pyruvate. Analysis of left ventricular (b: LVSWI post-bypass) and right ventricular (c: RVSWI post-bypass) stroke work indices in 30 patients (15 patients per group) at 4, 6 and 12 h recovery following cardiopulmonary bypass with lactate- vs. pyruvate-enriched cardioplegia (total 90 data points).130AUC: area under the ROC curve; CI: 95% confidence interval; LVSWI: left ventricular stroke work index; RVSWI: right ventricular stroke work index.