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. Author manuscript; available in PMC: 2018 Jan 29.
Published in final edited form as: Int Rev Cell Mol Biol. 2013;300:1–50. doi: 10.1016/B978-0-12-405210-9.00001-1

Figure 1.

Figure 1

Stem cell behavior proposed in invertebrate model systems. (A) Three possible cell division strategies: invariant asymmetric division (left); invariant symmetric division (middle); combination of asymmetric and symmetric divisions (right). (B) Cell-extrinsic (upper) and -intrinsic (lower) regulation of asymmetric cell division. (C) Two possible stem cell behaviors to replenish a new stem cell: symmetric division (upper) and dedifferentiation (lower).