Table 1. Conditions and quantities of drugs and excipients selected for formulation of Nanoemulsion and characterization .
| Nanoemulsion | ||
| Drug candidate | P60+CRB | Composition |
| Oil | Oleic Acid | 10% |
| Surfactant | Tween 20 | 20% |
| Co-surfactant | Glycerol | 3.52% |
| Aqueous Phase | Mili Q water | 66.48% |
| Label claim | 41 mg/ml | P60 = 11 mg/ml |
| CRB = 30 mg/ml | ||
| Formulation Parameters | ||
| Homogenization Speed | 10,000 rpm | |
| Homogenization Time | 30 min | |
| Time of Ultrasonication | 300 sec | |
| % Amplitude | 30% | |
| Charaterization Parameters | ||
| Droplet size | 58±1 nm | |
| PDI | 0.2±0.015 | |
| Zeta potential | -16±0.2 mV | |
Where, P60: Polyphenon 60; CRB: Cranberry; PDI: Particle distribution index