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. 2018 Jan 29;13(1):e0190447. doi: 10.1371/journal.pone.0190447

Fig 5. Transcription regulatory network of gene modules.

Fig 5

A: PPI network of DEGs. B: hub genes in the subnetwork of the blue module. C: Hub genes in the subnetwork of the yellow module. D: The transcriptional regulators of the main hub genes of the blue module. E: The transcriptional regulators of the main hub genes of the yellow module. The triangle represents the DEGs in each enriched module, the red color and the up-direction represent up-regulated DEGs; the blue color and the down-direction represent down-regulated DEGs. The size of the nodes was weighted by the power of the DEGs that interacted with transcriptional regulators.