Table 2. Significant differences in concentrations of amino acids among three groups of PD patients compared using Kruskal-Wallis test.
Amino acid | ePD n = 22 mean±SD (μmol/l); median |
aPD LID+ n = 28 mean±SD (μmol/l); median |
aPD LID- n = 23 mean±SD (μmol/l); median |
p- value |
---|---|---|---|---|
Alanine | 430.8±70.2; 430.6 | 382.2±107.0; 367.1 | 393.5±100.4; 383.6 | 0.048 |
Arginine | 109.4±25.4; 101.8 | 90.8±15.6; 92.0 | 92.9±19.8; 93.9 | 0.008 |
Phenylalanine | 67.9±9.4; 69.7 | 59.4±8.1; 59.3 | 63.2±9.6; 62.1 | 0.008 |
Threonine | 125.7±33.6; 116.6 | 145.0±35.1; 136.0 | 148.7±35.2; 148.2 | 0.021 |
ePD- early Parkinson’s disease stadium; aPD LID+ advanced Parkinson’s disease stadium with dyskinesia, aPD LID- advanced Parkinson’s disease stadium without dyskinesia.