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. 2018 Jan 29;13(1):e0192082. doi: 10.1371/journal.pone.0192082

Fig 1. A neutrophil driven response is observed early in diarrheal disease and drives transcriptional variation.

Fig 1

(A) Principal component analysis of transcriptional profiles from whole blood indicates clustering of HC profiles but no clustering according to infection type. (B) The first principal component is highly correlated with neutrophil percentages (r = 0.69, p < 2.2e-16). (C-E) Leukocyte subset percentages as a function of time elapsed between disease onset and blood RNA collection. * p < 0.01, *** p < 0.001, **** p < 1e-5, Wilcoxon rank-sum test (HC compared to all disease cases).