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. 2018 Jan 29;13(1):e0192266. doi: 10.1371/journal.pone.0192266

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© 2018 Yu et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — The changes in UPCR (A, C) and eGFR (B, D) during the follow-up period after cessation of the clinical study. From left to right, each box-plot represents the follow-up periods of 0-weeks, 4-weeks, 8-weeks, 12-weeks and 16-weeks of the trial phase, and 12-weeks, 24-weeks, 52-weeks, and the final visit by October 2016 of the observational phase. A. The p-value for tests of between two groups was 0.130. B. The p-value for tests of between-subjects effects was 0.543. C. The p-value for tests of between-subjects effects was 0.830. D. The p-value for tests of between-subjects effects was 0.488. Tac: Tacrolimus, RASi: renin-angiotensin-aldosterone system inhibitor, UPCR: urine protein to creatinine ratio, eGFR: estimated glomerular filtration rate by the equation of CKD-EPI. The p-value estimated by linear mixed effect model.