Table 1.
Characteristics of offspring | Siblings exposed to GDM in utero (n = 18) | Siblings not exposed to GDM in utero (n = 18) | P value |
---|---|---|---|
Current age (years) | 5.8 ± 1.4 | 9.4 ± 2.5 | <0.0001 |
Sex (male/female) | 11/7 | 10/8 | 0.999 |
Maternal age at delivery (years) | 34.4 ± 2.5 | 30.8 ± 2.4 | <0.0001 |
Delivery (NFSD/PSD/C-sec) | 6/0/12 | 5/1/11 | 0.999 |
Birth weight (kg) | 3.3 ± 0.4 | 3.2 ± 0.6 | 0.671 |
Current BMI Z-score | 0.19 ± 0.73 | 0.31 ± 0.86 | 0.594 |
Current HbA1C (%) |
5.3 ± 0.3 |
5.3 ± 0.2 |
0.326 |
Characteristics of mothers* |
During GDM pregnancy (n = 18) |
||
Age (years) | 34.4 ± 2.5 | ||
BMI before pregnancy (kg/m2) | 22.7 ± 2.4 | ||
BMI at delivery (kg/m2) | 28.6 ± 8.2 | ||
Cigarette smokers | None | ||
Gestational weeks at 50 g OGTT (weeks) | 26 ± 2 | ||
Glucose levels at 50 g OGTT (mg/dL) | 170 ± 26 | ||
Gestational weeks at 100 g OGTT (weeks) | 28 ± 2 | ||
Glucose levels at 100 g OGTT (mg/dL) | |||
0-hour | 97 ± 18 | ||
0.5-hour | 206 ± 40 | ||
2-hour | 178 ± 39 | ||
3-hour | 154 ± 34 | ||
Insulin treatments | 6 treated (33%) |
Maternal data during GDM pregnancy only were available.
Continuous data are presented as mean ± standard deviation and P values were calculated using paired t-test. Categorical data were presented in counts and tested with Pearson's Chi-square test. BMI Z-score were calculated according 2007 Korean National Growth Charts. NFSD, normal full-term spontaneous delivery; PSD, preterm spontaneous delivery; C-sec, Caesarean section.