Figure 5.

Effects of the U1 deletion on survival. Four individual sets of breeding experiments were performed to test potential effects of the U1 deletion on survival (A-D). The results from each breeding experiment were summarized with its average litter size, transmission ratios between individual genotypes, and sex ratios. The last row (2X Peg3) summarizes the numbers of heterozygote and/or homozygote mice presumably having a double dosage of Peg3 as well as the imprinting defects, which were measured by the DNA methylation status of the Peg3-DMR. Numbers in parentheses indicate the numbers of mice with 2X Peg3 and the imprinting defects in each genotype. Numbers in red indicate the unusual outcomes that deviate significantly from the expected frequencies.