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. 2017 Nov 27;12(10):865–874. doi: 10.1080/15592294.2017.1365207

Figure 1.

Figure 1.

a: QMSP assay results of the 78 ESCCs. The tumor tissues showed significantly high relative QMSP values compared with the adjacent normal tissues (P < 0.001, Mann–Whitney U test). b: The 78 ESCC tumors were divided into PAX5 high QMSP (n = 26) and low QMSP (n = 52) groups by the optimal cutoff value (QMSP = 16.0). PAX5 mRNA expression in the high QMSP group was significantly lower than that in the low QMSP group (P = 0.040, Mann–Whitney U test). Gene hypermethylation appeared to be one of the major mechanisms for the downregulation of PAX5 mRNA expression.