a: Influence of PAX5 methylation status on cisplatin-treated and untreated cases examined by Kaplan–Meier curves. Among the cisplatin-treated cases (n = 26), the PAX5 high QMSP group showed significantly poorer RFS (P < 0.001, log-rank test), while no significant difference was seen in the non-adjuvant chemotherapy cases (n = 52; P = 0.091, log-rank test). b: Influence of PAX5 methylation status on radiation-treated and untreated cases examined by Kaplan–Meier curves. The PAX5 methylation status did not affect the prognostic outcomes among the irradiated cases (P = 0.297, log-rank test).