Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
MiR-367 stimulated self-renewal of CSCs via blocking FBXW7 and releasing Let-7c repressed Wnt pathway, A-C. Reintroducing FBXW7, Let-7c or sh-TCF-4 into miR-367 overexpressed spheres cells all abolished its oncogenic roles in self-renewing. TCF-4 inhibition exerted similar effect as the combination of sh-TCF-4 and miR-367 did. D-E. Representative images of spheres from the 1st and 2nd generations were shown. ** p < 0.001,* p < 0.01, # p < 0.05.
