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. 2017 Oct 4;13(11):1969–1980. doi: 10.1080/15548627.2017.1371393

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Figure 5. — MAP2K2 and PLK1 are involved in the regulation of compound-induced neuronal autophagy. (A) The changes in LC3B-II upon the Cory and Cory B treatments, after silencing MAP2K2 and PLK1. (B) Quantifications of the LC3B-II:ACTB ratio in the Cory or (C) Cory B group. (D) The changes in SQSTM1 treated with Cory and Cory B, after the silencing of MAP2K2 and PLK1. (E) Quantifications of the SQSTM1:ACTB ratio in the Cory or (F) Cory B group. *p < 0.5; ***p < 0.001; ns, not significant; NT, nontargeting.