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. 2017 Dec 1;9(2):1843–1851. doi: 10.18632/oncotarget.22828

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Copyright: © 2018 Du et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) The migration capability of NPC cells regulated by lncRNA-n326322 was determined by wound-healing assays. (B) Transwell assay with or without matrigel showed that upregulation of lncRNA-n326322 increased cell invasion and migration in 6-10B cells, whereas downregulation of lncRNA-n326322 suppressed cell invasion and migration capability in CNE-2 cells. ^**P < 0.05 compared with control. (C) Western blot results demonstrated that the overexpression of lncRNA-n326322 induced the expression of p-ERK, MMP2 and MMP9, and the knockdown of lncRNA-n326322 inhibited the expression of p-ERK, MMP2 and MMP9.