Table 1. Echocardiographic and hemodynamic measurements at 3 days (MI-3d) and 7 days (MI-7d) after AMI.
Parameters | After 3 d | After 7 d | ||
---|---|---|---|---|
Sham-3d (n =10) | MI-3d (n =9) | Sham-7d (n =10) | MI-7d (n =7) | |
Echocardiography$ | ||||
LVEDd (mm) | 3.31 ± 0.28 | 4.39 ± 0.31*** | 3.32 ± 0.40 | 5.36 ± 0.50### |
LVESd (mm) | 1.66 ± 0.31 | 3.45 ± 0.75*** | 1.64 ± 0.28 | 4.75 ± 0.63### |
ExLVDd (mm) | 4.73 ± 0.40 | 5.40 ± 0.48** | 4.64 ± 0.37 | 6.22 ± 0.41### |
LVAWs (mm) | 1.42 ± 0.12 | 0.40 ± 0.10*** | 1.35 ± 0.12 | 0.41 ± 0.23### |
LVAWd (mm) | 0.85 ± 0.16 | 0.39 ± 0.16*** | 0.79 ± 0.11 | 0.33 ± 0.14### |
FS (%) | 49.84 ± 8.56 | 21.71 ± 15.59*** | 49.81 ± 10.49 | 11.69 ± 5.79### |
Hemodynamics$ | ||||
HR (beats/min) | 344.75 ± 17.47 | 347.78 ± 29.55 | 366.22 ± 20.50 | 343.57 ± 35.99 |
SBP (mm Hg) | 112.13 ± 25.33 | 84.67 ± 9.99** | 110.56 ± 18.21 | 81.57 ± 13.20## |
DBP (mm Hg) | 79.63 ± 17.79 | 69.33 ± 11.03 | 74.78 ± 13.74 | 67.29 ± 11.01 |
LVSP (mm Hg) | 113.75 ± 22.60 | 92.67 ± 9.98* | 105.44 ± 16.74 | 88.86 ± 12.21 |
+dP/dt (mm Hg/s) | 9981.5 ± 2502.60 | 6243.89 ± 1401.72*** | 8193.78 ± 1821.76 | 4847.29 ± 1386.83## |
-dP/dt (mm Hg) | 9243.50 ± 2205.78 | 5607.00 ± 1816.97*** | 8697.78 ± 1703.62 | 3883.00 ± 728.92### |
*p < 0.05 versus Sham-3d; **p < 0.01 versus Sham-3d; ***p < 0.001 versus Sham-3d
#p < 0.05 versus Sham-7d; ##p < 0.01 versus Sham-7d; ###p < 0.001 versus Sham-7d
$, echocardiography parameters; BW, body weight; LVEDd, left ventricular internal end-diastolic diameters; LVESd, left ventricular internal end-systolic diameter; ExLVDd, external left ventricular diastolic diameter; LVAWs, left ventricular systolic anterior wall thickness; LVAWd, left ventricular diastolic anterior wall thickness; FS, fractional shortening. Hemodynamic parameters, HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; LVSP, left ventricular systolic pressure; dP/dtmax, maximal rates of rise in left ventricular pressure; dP/dtmin, maximal rates of fall in left ventricular pressure.