Table 1. Correlation analysis between miR-125b expression and clinical indicators of patients.
Clinicopathological characteristics | Number of cases | mean1 | SD2 | P-value |
---|---|---|---|---|
Gender | 0.044 | |||
Male | 22 | -1.341 | 1.794 | |
Female | 7 | 0.494 | 1.852 | |
Age | 0.425 | |||
≤60 | 16 | -0.628 | 1.819 | |
>60 | 13 | -1.231 | 2.119 | |
Venous Invasion | 0.968 | |||
Positive | 15 | -0.913 | 1.591 | |
Negative | 14 | -0.883 | 2.331 | |
Perineural Invasion | 0.970 | |||
Positive | 4 | -0.932 | 1.792 | |
Negative | 25 | -0.893 | 2.005 | |
Tumor location | 0.294 | |||
Cardia | 7 | -1.639 | 0.707 | |
Gastric Body | 4 | 0.351 | 1.550 | |
Gastric Antrum | 18 | -0.888 | 2.246 | |
Borrmann stage | 0.727 | |||
I+II | 15 | -0.772 | 1.755 | |
III+IV | 14 | -1.034 | 2.192 | |
pT stage | 0.954 | |||
T1+T2+T3 | 6 | -0.856 | 1.894 | |
T3+T4 | 23 | -0.909 | 2.002 | |
pN stage | 0.045* | |||
N0+N1 | 12 | -0.042 | 1.815 | |
N2+N3 | 17 | -1.503 | 1.851 | |
pM stage | ||||
M0 | 28 | -0.971 | 1.942 | |
M1 | 1 | 1.131 | ||
pTNM stage | 0.511 | |||
I+II | 6 | -0.441 | 1.788 | |
III+IV | 23 | -1.018 | 2.006 | |
Histologic grade | 0.282 | |||
Well | 10 | -1.501 | 2.283 | |
Poor | 19 | -0.581 | 1.726 | |
HER2 amplification | 0.039* | |||
Positive | 6 | -2.629 | 1.928 | |
Negative | 23 | -0.447 | 1.717 |
1: mean of Log2 (C/N); 2: Standard Definition of Log2 (C/N); C: normalized expression of cancer tissues; N: normalized expression of adjacent noncancerous tissues.