Table 1. Basic SNPs in APOB gene summary of all study participants.
SNP rs# | Chr | Position | Band | Alleles A/B | Role | Amino acid change | Amino acid position | H-W p | OR(95%CI) | p |
---|---|---|---|---|---|---|---|---|---|---|
rs1042034 | 2 | 21225281 | 2p24.1 | T/C | Coding exon | S/? | 4338 | 0.3519 | 1.29(1.02-1.63) | 0.03 |
rs1801702 | 2 | 21225485 | 2p24.1 | G/C | Coding exon | R/T | 4270 | 1 | 0.92(0.47-1.81) | 0.807 |
rs693 | 2 | 21232195 | 2p24.1 | A/G | Coding exon | T/? | 2515 | 0.6686 | 1.44(0.97-2.12) | 0.069 |
rs673548 | 2 | 21237544 | 2p24.1 | G/A | Intron (boundary) | -- | -- | 0.3531 | 1.28(1.02-1.62) | 0.034 |
rs3791981 | 2 | 21245367 | 2p24.1 | G/A | Intron | -- | -- | 1 | 1.09(0.66-1.8) | 0.744 |
rs679899 | 2 | 21250914 | 2p24.1 | G/A | Coding exon | A/? | 618 | 0.8514 | 1.22(0.93-1.6) | 0.155 |
rs512535 | 2 | 21267782 | 2p24.1 | T/C | Promoter | -- | -- | 0.6662 | 1.18(0.92-1.5) | 0.192 |
A/B stands for minor/major alleles on the control sample frequencies.
SNPs are excluded at 5% HWE P level.
p < 0.05 indicates statistical significance.