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. 2017 Dec 19;9(2):2268–2278. doi: 10.18632/oncotarget.23405

Table 1. IC50 of anticancer drugs in Reh cells and resistant cells.

Drugs IC50 (μg/mL) aRelative resistance bRelative resistance
Reh Reh-6MPR Reh-6TGR
6-MP 0.18±0.02 174.23±16.75*** 125.73±3.54*** 968 699
6-TG 0.09±0.01 104.50±2.79*** 86.05±5.82*** 1161 956
MTX 0.005±0.0006 0.0039±0.0001 0.004±0.0002 0.78 0.80
AraC 0.0024±0.0001 0.0018±0.0002 0.0016±0.0001 0.75 0.67

Values are given as mean ± SD. IC50 of resistant cells to 6-MP and 6-TG differed significantly from Reh cells, ***P<0.001 compared with Reh group. aRelative resistance was obtained by dividing the IC50 mean value of Reh cells by the IC50 value of Reh-6MPR cells; bRelative resistance was obtained by dividing the IC50 mean value of Reh cells by the IC50 value of Reh-6TGR cells.